Pluripotent stem cell (PSC) research is an expanding field that has the potential to change the way human diseases are studied and treated. See More The ability to differentiate embryonic stem (ES) cells and induced pluripotent stem (iPS) cells to specific downstream cell types opens up new avenues for drug development and regenerative medicine. From generation of iPS cells to maintenance, differentiation, characterization, and cryopreservation of ES and iPS cells, see how you can "Maximize Your Pluripotential" with the most complete, defined system for ES and iPS cell culture. For help with your hPSC workflow decision making, use our infographics to find the right reagents for you.
Read this mini-review to learn more about Pluripotent Stem Cells.See Less
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LUBAC Is Essential for Embryogenesis by Preventing Cell Death and Enabling Hematopoiesis
Researchers showed, by creating HOIL-1-deficient mice, that HOIL-1 is as essential for linear ubiquitin chain assembly complex (LUBAC) function as HOIP, albeit for different reasons: whereas HOIP is the catalytically active component of LUBAC, HOIL-1 is required for LUBAC assembly, stability and optimal retention in the TNFR1 signaling complex, thereby preventing aberrant cell death.ESC & iPSC News Volume 13.16, April 25, 2018. Read full issue at