Pluripotent stem cell (PSC) research is an expanding field that has the potential to change the way human diseases are studied and treated. See More The ability to differentiate embryonic stem (ES) cells and induced pluripotent stem (iPS) cells to specific downstream cell types opens up new avenues for drug development and regenerative medicine. From generation of iPS cells to maintenance, differentiation, characterization, and cryopreservation of ES and iPS cells, see how you can "Maximize Your Pluripotential" with the most complete, defined system for ES and iPS cell culture. For help with your hPSC workflow decision making, use our infographics to find the right reagents for you.
Read this mini-review to learn more about Pluripotent Stem Cells.See Less
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Pseudouridylation of tRNA-Derived Fragments Steers Translational Control in Stem Cells
"The authors showed that a pseudouridylation-driven posttranscriptional program steers translation control to impact stem cell commitment during early embryogenesis. PUS7 inactivation in embryonic stem cells impaired tRNA-derived small fragment-mediated translation regulation, leading to increased protein biosynthesis and defective germ layer specification."ESC & iPSC News Volume 13.14, April 11, 2018. Read full issue at