Small Molecules

  • Featured CHIR99021

    CHIR99021

    WNT pathway activator; Inhibits GSK3
  • Featured Dorsomorphin

    Dorsomorphin

    BMP and AMPK pathway inhibitor; Inhibits ALK2, ALK3, ALK6, and AMPK
  • Featured Y-27632 (Dihydrochloride)

    Y-27632

    RHO/ROCK pathway inhibitor; Inhibits ROCK1 and ROCK2
  • Featured SB431542

    SB431542

    Activin/BMP/TGF-β pathway inhibitor; Inhibits ALK4, ALK5, and ALK7
  • Featured UM729

    UM729

    Pyrimido-indole derivative that enhances HSC self-renewal in vitro
  • AICAR

    AICAR

    AMPK activator
  • Sirtinol

    Sirtinol

    Epigenetic modifier; Inhibitor of Sir2p, SIRT1, and SIRT2
  • (Z)-4-Hydroxytamoxifen

    (Z)-4-Hydroxytamoxifen

    Estrogen signaling pathway modulator; Modulates selective estrogen receptor and estrogen-related receptor
  • KU0060648

    KU0060648

    NHEJ pathway inhibitor; Inhibits DNA-dependent protein kinase (DNA-PK)
  • Nocodazole

    Nocodazole

    Microtubule polymerization inhibitor; Inhibits beta-tubulin
  • NU7441

    NU7441

    NHEJ pathway inhibitor; Inhibits DNA-dependent protein kinase (DNA-PK)
  • RS-1

    RS-1

    HDR pathway enhancer; Enhances RAD51