Small Molecules

  • Featured CHIR99021

    CHIR99021

    WNT pathway activator; Inhibits GSK3
  • Featured Y-27632 (Dihydrochloride)

    Y-27632

    RHO/ROCK pathway inhibitor; Inhibits ROCK1 and ROCK2
  • AICAR

    AICAR

    AMPK activator
  • Sirtinol

    Sirtinol

    Epigenetic modifier; Inhibitor of Sir2p, SIRT1, and SIRT2
  • (Z)-4-Hydroxytamoxifen

    (Z)-4-Hydroxytamoxifen

    Estrogen signaling pathway modulator; Modulates selective estrogen receptor and estrogen-related receptor
  • KU0060648

    KU0060648

    NHEJ pathway inhibitor; Inhibits DNA-dependent protein kinase (DNA-PK)
  • Nocodazole

    Nocodazole

    Microtubule polymerization inhibitor; Inhibits beta-tubulin
  • NU7441

    NU7441

    NHEJ pathway inhibitor; Inhibits DNA-dependent protein kinase (DNA-PK)
  • RS-1

    RS-1

    HDR pathway enhancer; Enhances RAD51
  • SCR7

    SCR7

    NHEJ pathway inhibitor; inhibits DNA ligase IV
  • BSI-201

    BSI-201

    Cysteine-containing protein modifier; Inhibits growth of triple-negative breast cancer cells
  • CGP77675

    CGP77675

    Src family kinases inhibitor; Inhibits Src, LCK, Yes, Cdc2, EGFR, VEGFR, v-Abl, and FAK