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Small Molecules

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1-Azakenpaullone

Inhibits glycogen synthase kinase 3β (GSK3β)
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Tamoxifen

Estrogen signaling pathway modulator; Modulates selective estrogen receptor and estrogen-related receptor
New
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UM729

Pyrimido-indole derivative that enhances HSC self-renewal in vitro
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SB431542

Activin/BMP/TGF-β pathway inhibitor; Inhibits ALK4, ALK5, and ALK7
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(+)-Bay K8644

L-type calcium channel inhibitor
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(-)-Blebbistatin

Non-muscle myosin II (NM II) ATPase inhibitor
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(-)-Epigallocatechin Gallate

Antioxidant and epigenetic modifier; Inhibits DNA methyltransferases (DNMTs)
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(-)-Indolactam V

Protein kinase C (PKC) activator
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(S)-MG132

Ubiquitin-proteasome inhibitor; NF-kB pathway inhibitor; IκB activator
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(±)-Flurbiprofen

PI3K/AKT pathway inhibitor; Inhibits COX-1 and COX-2
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(±)-Nutlin-3

p53 pathway activator; Inhibits MDM2
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1-Oleoyl Lysophosphatidic Acid

Lysophosphatidic acid (LPA)1 and LPA2 agonist