Small Molecules

  • FK506

    FK506

    Calcineurin/NFAT pathway inhibitor; Binds FKBP-12
  • LY2228820

    LY2228820

    p38 MAP kinase (MAPK) inhibitor
  • NU7026

    NU7026

    NHEJ pathway inhibitor; Inhibits DNA-dependent protein kinase (DNA-PK)
  • MLN4924

    MLN4924

    Inhibits NEDD8-activating enzyme
  • 4-Octyl Itaconate

    4-Octyl Itaconate

    Activates nuclear factor erythroid 2-related factor 2 (Nrf2) protein
  • SMER28

    SMER28

    Enhances mammalian autophagy
  • 3-Methyladenine

    3-Methyladenine

    PI3K/AKT pathway inhibitor
  • Delphinidin

    Delphinidin

    Inhibits EGFR and VEGFR
  • Bafilomycin A1

    Bafilomycin A1

    Inhibits autophagy and vacuolar H+-ATPase (V-ATPase)
  • 1-Azakenpaullone

    1-Azakenpaullone

    Inhibits glycogen synthase kinase 3β (GSK3β)
  • Tamoxifen

    Tamoxifen

    Estrogen signaling pathway modulator; Modulates selective estrogen receptor and estrogen-related receptor
  • UM729

    UM729

    Pyrimido-indole derivative that enhances HSC self-renewal in vitro