hPSC-Derived Endoderm Cell Research
Differentiate human pluripotent stem cells (hPSCs) into cells of the endoderm lineage with our specialized cell culture media. STEMdiff™ is a line of culture medium kits specifically optimized for hPSC differentiation—to reproducibly differentiate multiple human embryonic stem (ES) and induced pluripotent stem (iPS) cell lines to 2D cell types and 3D organoid models originating from all three embryonic germ layers. Use our new interactive STEMdiff™ product explorer to find specific differentiation kits for your tissue of interest. Further characterize the downstream cells with our high-quality verified antibodies.
Products
Cell Culture Media and Supplements 4 (16)
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STEMdiff™ Branching Lung Organoid Maturation Kit
Serum-free medium for maturation of hPSC-derived branching lung organoids -
STEMdiff™ Branching Lung Organoid Kit
Serum-free media for generation and maturation of branching lung organoids from human ES and iPS cells -
STEMdiff™ Intestinal Organoid Growth Medium
Serum-free medium for long-term maintenance of hPSC-derived human intestinal organoids -
STEMdiff™ Intestinal Organoid Kit
Serum-free medium kit for establishment and maintenance of human intestinal organoids from hPSCs
Tissue and Cell Culture Dissociation Reagents 4 (1)
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Gentle Cell Dissociation Reagent
cGMP, enzyme-free cell dissociation reagent
Matrices and Substrates 4 (2)
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CellAdhere™ Dilution Buffer
Dilution buffer for matrix proteins, e.g. Vitronectin XF™ -
Vitronectin XF™
Defined, xeno-free matrix that supports the growth and differentiation of human pluripotent stem cells under serum-free, feeder-free conditions
Cytokines and Proteins 4 (25)
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Human/Mouse/Rat Recombinant Follistatin-Resistant Activin A, ACF
Follistatin-resistant Activin A, animal component-free -
Human Recombinant IGF-I LR3, ACF
Insulin-like growth factor 1 long arginine 3, animal component-free -
Human Recombinant R-Spondin-1 (E. coli-expressed), ACF
R-Spondin-1, animal component-free -
Human Recombinant BMP-4, ACF
Bone morphogenetic protein 4, animal component-free
Small Molecules 4 (5)
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Sodium Butyrate
Epigenetic modifier; Inhibits histone deacetylase -
LDN193189
BMP pathway inhibitor; Inhibits ALK1, ALK2, ALK3, and ALK6 -
IWR-1-endo
WNT pathway inhibitor; AXIN2 stabilizer -
(-)-Indolactam V
Protein kinase C (PKC) activator
Antibodies 4 (10)
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Anti-Human TRA-2-54 Antibody, Clone TRA-2-54/2J
Mouse monoclonal IgG1 antibody against human, chimpanzee, gibbon TRA-2-54 (tissue non-specific alkaline phosphatase) -
Anti-Human TRA-2-49 Antibody, Clone TRA-2-49/6E
Mouse monoclonal IgG1 antibody against human, chimpanzee, gibbon TRA-2-49 (tissue non-specific alkaline phosphatase) -
Anti-Mouse OCT4 (OCT3) Antibody, Clone 40
Mouse monoclonal IgG1 antibody against human, mouse OCT4 (OCT3) -
Anti-Human CD184 (CXCR4) Antibody, Clone 12G5
Mouse monoclonal IgG2a antibody against human, rhesus, cynomolgus CD184 (CXCR4)
Buffers and Solutions 4 (1)
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D-PBS (Without Ca++ and Mg++)
Dulbecco’s phosphate-buffered saline without calcium and magnesium
Cultureware and General Supplies 4 (1)
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Axygen® Sealing Film for Quantitative Real-Time PCR (qPCR)
Non-sterile, ultra-clear, pressure-sensitive sealing film for quantitative real-time PCR (qPCR)
Cell Engineering and Molecular Tools 4 (2)
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Human Pluripotent Stem Cell-Derived Endoderm qPCR Array
For characterizaton of hPSC-derived progenitor cells of definitive endoderm, hepatic, intestinal, or pancreatic lineages -
qPCR Master Mix Kit
For probe-based assays and arrays
