All-Trans Retinoic Acid
Retinoid pathway activator; Activates retinoic acid receptor (RAR)
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Overview
DIFFERENTIATION
· Promotes differentiation of motor neurons from mouse and human pluripotent stem cells (Dimos et al., Wichterle et al.).
· Promotes differentiation of neurons from neural stem cells (Takahashi et al.).
· Promotes differentiation of pancreatic progenitors from human embryonic stem (ES) cells (D'Amour et al.).
· Promotes differentiation of adipocytes from mouse ES cells (Dani et al.).
· Promotes differentiation of ventricular cardiomyocytes from mouse ES cells (Wobus et al.).
· Promotes terminal differentiation of granulocytes (Collins).
CANCER RESEARCH
· Promotes maturation of blast cells in differentiation therapy of acute promyelocytic leukemia (Huang et al.).
Protocols and Documentation
Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.
Applications
This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.
Resources and Publications
Educational Materials (5)
Publications (10)
Abstract
Abstract
Abstract
Quality Statement:
PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED. FOR ADDITIONAL INFORMATION ON QUALITY AT STEMCELL, REFER TO WWW.STEMCELL.COM/COMPLIANCE.