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Mesenchymal Stem and Progenitor Cell Research

In culture, mesenchymal stem cells (MSCs) are defined as plastic-adherent, fibroblast-like cells which are able to self-renew and differentiate into at least adipose, bone and cartilage cells. See More Optimized cell culture reagents are available for the efficient and robust differentiation of MSCs to adipocytes, osteoblasts and chondrocytes. For best results, perform in vitro trilineage differentiation of MSCs after culturing and cryopreserving cells with standardized MesenCult™ media. Use MesenCult™-ACF Medium and MesenCult™-ACF Freezing Medium for the animal component-free culture and cryopreservation of human mesenchymal stem cells, or the MesenCult™ Expansion Kit (Mouse) for highly enriched mouse MSC cultures as early as passage 0.

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Cell Culture Media and Supplements (46)

Buffers and Solutions (41)

Cultureware and General Supplies (42)

Small Molecules (429)

  • IBMX

    IBMX

    cAMP pathway activator; Inhibits cyclic nucleotide phosphodiesterases
  • Genistein

    Genistein

    NF-kB, AMPK, and tyrosine kinase pathway inhibitor; Inhibits tyrosine kinase and topoisomerase II and activates PPARγ
  • Troglitazone

    Troglitazone

    NF-kB pathway inhibitor; Activates PPARγ
  • Indomethacin

    Indomethacin

    Inhibits COX-1 and COX-2

Cytokines (423)

Standardization Tools (41)