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EasySep™

EasySep™ Cell Separation

A Smarter, More Efficient Way to Isolate Cells

Working efficiently is key to overcome the demands of scientific research. That’s why our scientists have developed a smarter, more efficient way to isolate cells. EasySep™ combines the specificity of monoclonal antibodies with the simplicity of a column-free magnetic system for fast and easy isolation of highly purified cells that are ready for downstream applications. This versatile immunomagnetic cell separation technology enables positive selection, negative selection, or cell depletion.

EasySep™ can be used to isolate cells in as little as 8 minutes from a variety of species (ex. human, mouse, non-human primate, rat, rabbit, cow and pig) and sample sources (ex. splenocytes, lymph nodes, PBMCs, whole blood, cord blood, bone marrow and leukapheresis samples).

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Fast and Easy Cell Isolation with EasySep™

How Does EasySep™ Cell Separation Work?

Cells are targeted for either removal (negative selection and depletion) or positive selection using antibody complexes directed to specific cell surface antigens. The antibody complexes link targeted cells to EasySep™ magnetic particles. Labeled cells are pulled to the sides of the tube when the sample is placed in an EasySep™ cell separation magnet, while untouched cells can be simply poured or pipetted off into a new tube.

See how it works

How Does EasySep™ Enable Research?

Is EasySep™ a Well-Accepted Cell Separation Method?

Since its launch in 2002, EasySep™ has been used by thousands of labs worldwide to quickly and easily isolate highly purified cells for a wide variety of applications. More immunologists are making the switch to EasySep™ so they can accomplish more with their time in the lab.

Hear from Current Users

View Publication Highlights

Why Use EasySep™ to Isolate Cells?

  • Isolate cells in as little as 8 minutes with a simple pour.
  • Achieve up to 99% cell purities with high recoveries.
  • Obtain viable, functional cells without the need for columns and washes.
  • Isolate cells from virtually any sample source, including whole blood and Leuko Paks.

Switching your cell separation technology to EasySep™ is easier than you think.
View frequently asked questions

Already an EasySep™ user? Explore our next-generation EasySep™ kits and make sure your lab is using the most up-to-date kits.

EasySep™ for Human Cell Separation

EasySep™
Human Cell Isolation Kits

EasySep™ Human Cell Isolation Kits

Typical Sample Source:

PBMCs, Leuko Paks

Protocol Time:

As Little As 8 Minutes

Selection Method:

Negative Selection

Features/Advantages:

  • High purity (up to 98%)
  • Column-free
  • Untouched cells immediately ready for downstream analysis
  • Can be fully automated using RoboSep™

EasySep™
Human Positive Selection Kits

EasySep™ Human Positive Selection Kits

Typical Sample Source:

PBMCs, Leuko Paks

Protocol Time:

As Little As 15 Minutes

Selection Method:

Positive Selection

Features/Advantages:

  • High purity (up to 99%)
  • Column-free
  • Can be fully automated using RoboSep™

EasySep™ Direct Cell Isolation Kits

EasySep™ Direct

Typical Sample Source:

Whole Blood

Protocol Time:

As Little As 20 Minutes

Selection Method:

Negative Selection

Features/Advantages:

  • 99.9% RBC depletion without density gradient centrifugation, lysis or sedimentation
  • High purity (up to 99%)
  • Column-free
  • Untouched cells immediately ready for downstream analysis

EasySep™ Release Cell Separation Kits

EasySep™ Release

Typical Sample Source:

PBMCs, Leuko Paks

Protocol Time:

As Little As 29 Minutes

Selection Method:

Positive Selection

Features/Advantages:

  • High purity (up to 99%)
  • Column-free
  • Magnetic particle-free cells
  • Flexibility to perform sequential positive selections to isolate unique and rare cell types
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EasySep™ for Mouse and Rat Cell Separation

EasySep™
Mouse Cell Isolation Kits

Typical Sample Source:

Spleen, Bone Marrow, Whole Blood, Lymph Nodes

Protocol Time:

As Little As 15 Minutes

Selection Method:

Negative Selection

Features/Advantages:

  • Fast and easy
  • High purity (up to 98%)
  • Column-free
  • Untouched cells immediately ready for downstream analysis
  • Can be fully automated using RoboSep™

EasySep™
Mouse Positive Selection Kits

Typical Sample Source:

Spleen, Bone Marrow, Whole Blood, Lymph Nodes

Protocol Time:

As Little As 15 Minutes

Selection Method:

Positive Selection

Features/Advantages:

  • Fast and easy
  • High purity (up to 99%)
  • Column-free
  • Can be fully automated using RoboSep™

EasySep™
Rat Cell Isolation Kits

Typical Sample Source:

Spleen, Lymph Nodes, Whole Blood

Protocol Time:

As Little As 13 Minutes

Selection Method:

Negative Selection

Features/Advantages:

  • Fast and easy
  • High purity (up to 99%)
  • Column-free
  • Untouched cells immediately ready for downstream analysis
  • Can be fully automated using RoboSep™
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EasySep™ for Other Species

EasySep™ cell separation technology can also be used to isolate cells from a variety of other species, including non-human primate, rabbit, cow and pig.
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