Human Recombinant FGF-9

Fibroblast growth factor 9

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Fibroblast growth factor 9
From: 205 USD

Overview

Fibroblast growth factor (FGF) 9 is a pleiotropic member of the FGF family. FGFs are heparin-dependent regulators of cell proliferation and differentiation (Itoh & Ornitz). FGF-9 signals by binding FGFR3 (IIIb) and the IIIc splice variants of the FGFR1, FGFR2, and FGFR3 receptors (Santos-Ocampo et al.; Mohammadi et al.; Plotnikov et al.). In mice, deletion of FGF-9 is lethal and expression of FGF-9 affects development of the skeleton, cerebellum, lungs, heart, vascular system, digestive tract, and testes (Colvin et al.; Harada et al.; Lin et al.). Altered levels of FGF-9 have also been reported in various types of human cancers (Leushacke et al.; Abdel-Rahman et al.).
Alternative Names:
Fibroblast growth factor-9, GAF, Glia-activating factor, HBGF-9
Cell Type:
Mesenchymal Stem and Progenitor Cells; Mesenchymal Cells, PSC-Derived; Airway Cells
Species:
Human
Area of Interest:
Respiratory Research; Organoids; Stem Cell Biology; Neuroscience
Molecular Weight:
23.4 kDa
Purity:
≥ 95%

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Data and Publications

Data

(A) The biological activity of Human Recombinant FGF-9 was tested by its ability to promote the proliferation of 3T3 cells. Cell proliferation was measured using a fluorometric assay method. The EC50 is defined as the effective concentration of the growth factor at which cell proliferation is at 50% of maximum. The EC50 in the example above is less than 2 ng/mL. (B) 2 μg of Human Recombinant FGF-9 was resolved with SDS-PAGE under reducing (+) and non-reducing (-) conditions and visualized by Coomassie Blue staining. Human Recombinant FGF-9 has a predicted molecular mass of 23.4 kDa.

STEMCELL TECHNOLOGIES INC.’S QUALITY MANAGEMENT SYSTEM IS CERTIFIED TO ISO 13485. PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED.