IDE2

Activin/BMP/TGF-β pathway activator

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Activin/BMP/TGF-β pathway activator
From: 111 USD

Overview

Inducer of definitive endoderm 2 (IDE2) induces differentiation of mouse or human pluripotent stem cells (PSCs) by activating SMAD2 phosphorylation and NODAL expression (Borowiak et al.). At EC₅₀ = 223nM, SOX17 expression was induced in mouse ES cells.

DIFFERENTIATION
· Induces definitive endoderm from mouse or human ES cells in the absence of Activin A, NODAL, or feeder cells (Borowiak et al.).
Alternative Names:
Not applicable
CAS Number:
1136466-93-7
Chemical Formula:
C₁₂H₂₀N₂O₃
Molecular Weight:
240.3 g/mol
Purity:
≥ 98%
Pathway:
Activin/Nodal/TGFβ

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This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.

STEMCELL TECHNOLOGIES INC.’S QUALITY MANAGEMENT SYSTEM IS CERTIFIED TO ISO 13485. PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED.