IDE2

Activin/BMP/TGF-β pathway activator
Catalog #
72522_C
Activin/BMP/TGF-β pathway activator
From: 118 USD

Overview

Inducer of definitive endoderm 2 (IDE2) induces differentiation of mouse or human pluripotent stem cells (PSCs) by activating SMAD2 phosphorylation and NODAL expression (Borowiak et al.). At EC₅₀ = 223nM, SOX17 expression was induced in mouse ES cells.

DIFFERENTIATION
· Induces definitive endoderm from mouse or human ES cells in the absence of Activin A, NODAL, or feeder cells (Borowiak et al.).
Alternative Names
Not applicable
Cell Type
Endoderm, PSC-Derived, Pluripotent Stem Cells
Species
Human, Mouse, Rat, Non-Human Primate, Other
Application
Differentiation
Area of Interest
Epithelial Cell Biology, Stem Cell Biology
CAS Number
1136466-93-7
Chemical Formula
C₁₂H₂₀N₂O₃
Molecular Weight
240.3 g/mol
Purity
≥ 98%
Pathway
Activin/Nodal/TGFβ

Related Products

Scientific Resources

Product Documentation

Document Type Product Name Catalog # Lot # Language
Document Type
Product Information Sheet
Product Name
IDE2
Catalog #
72522, 72524
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
IDE2
Catalog #
72522, 72524
Lot #
All
Language
English

Educational Materials(3)

Brochure
Small Molecules for Stem Cell Research
Wallchart
Small Molecules, Big Impact in Cancer Research
Mini Review
Small Molecules

Product Applications

This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.

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