IDE2

Activin/BMP/TGF-β pathway activator

IDE2

Activin/BMP/TGF-β pathway activator

From: 135 USD
Catalog #
72522_C
Activin/BMP/TGF-β pathway activator

Overview

Inducer of definitive endoderm 2 (IDE2) induces differentiation of mouse or human pluripotent stem cells (PSCs) by activating SMAD2 phosphorylation and NODAL expression (Borowiak et al.). At EC₅₀ = 223nM, SOX17 expression was induced in mouse ES cells.

DIFFERENTIATION
· Induces definitive endoderm from mouse or human ES cells in the absence of Activin A, NODAL, or feeder cells (Borowiak et al.).
Alternative Names
Not applicable
Cell Type
Endoderm, PSC-Derived, Pluripotent Stem Cells
Species
Human, Mouse, Rat, Non-Human Primate, Other
Application
Differentiation
Area of Interest
Epithelial Cell Biology, Stem Cell Biology
CAS Number
1136466-93-7
Chemical Formula
C₁₂H₂₀N₂O₃
Molecular Weight
240.3 g/mol
Purity
≥ 98%
Pathway
Activin/Nodal/TGFβ

Protocols and Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type
Product Name
Catalog #
Lot #
Language
Product Name
IDE2
Catalog #
72522, 72524
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
IDE2
Catalog #
72522, 72524
Lot #
All
Language
English

Applications

This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.

Resources and Publications

Educational Materials (2)

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