Genome Editing
The use of genome editing tools to generate specific changes to the DNA sequence of human pluripotent stem cells (hPSCs), by either introducing or correcting mutations, provides more accurate modeling of human disease when the gene-edited hPSCs are subsequently differentiated into human-derived tissues.
Products
Cell Culture Media and Supplements 4 (7)
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StemSpan™-AOF
cGMP medium, for culture and expansion of human hematopoietic cells -
IntestiCult™ Organoid Growth Medium (Human)
Cell culture medium for establishment and maintenance of human intestinal organoids -
CloneR™2
Defined supplement for improving survival of human ES and iPS cells in single-cell workflows -
ImmunoCult™-XF T Cell Expansion Medium
Serum-free and xeno-free medium for the expansion of human T cells
Primary and Cultured Cells 4 (25)
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Human Mobilized Peripheral Blood Leukopak, G-CSF, Fresh
Primary human cells, fresh -
Diseased Human Peripheral Blood Products, Myelofibrosis (MF)
Primary human cells, fresh or frozen -
Diseased Human Peripheral Blood Products, Multiple Myeloma (MM)
Primary human cells, fresh or frozen -
Diseased Human Peripheral Blood Products, Mantle Cell Lymphoma (MCL)
Primary human cells, fresh or frozen
Genome Editing and Molecular Tools 4 (10)
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CellPore™ Transfection Kit 300
Transfection & intracellular delivery kit -
ArciTect™ Cas9-eGFP Nuclease
Enhanced green fluorescent protein (eGFP)-tagged Cas9 nuclease for the generation of double-strand breaks in CRISPR-Cas9 genome editing -
ArciTect™ sgRNA
Custom-designed single guide RNA for CRISPR-Cas9 genome editing -
ArciTect™ Annealing Buffer (5X)
For guide RNA generation in CRISPR-Cas9 genome editing
Instruments and Software 4 (1)
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CellPore™ Transfection System
Cell mechanoporation system for transfection & intracellular delivery
Cultureware and General Supplies 4 (2)
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Costar® Microcentrifuge Tubes
Non-sterile, clear, polypropylene snap-cap microcentifuge tubes -
Axygen® Thin-Wall PCR Tubes
Non-sterile, clear, RNase/DNase-free, polypropylene conical tubes with caps
Small Molecules 4 (7)
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KU0060648
NHEJ pathway inhibitor; Inhibits DNA-dependent protein kinase (DNA-PK) -
Nocodazole
Microtubule polymerization inhibitor; Inhibits beta-tubulin -
NU7441
NHEJ pathway inhibitor; Inhibits DNA-dependent protein kinase (DNA-PK) -
RS-1
HDR pathway enhancer; Enhances RAD51
