Genome Editing

The use of genome editing tools to generate specific changes to the DNA sequence of human pluripotent stem cells (hPSCs), by either introducing or correcting mutations, provides more accurate modeling of human disease when the gene-edited hPSCs are subsequently differentiated into human-derived tissues.

Products

Cell Culture Media and Supplements (42)

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mTeSR™1

cGMP, feeder-free maintenance medium for human ES and iPS Cells
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CloneR™

Defined supplement for single-cell cloning of human ES and iPS cells

Molecular Biology (49)

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hPSC Genetic Analysis Kit

qPCR analysis kit for detecting the majority of karyotypic abnormalities reported in human ES and iPS cells
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ArciTect™ Cas9 Nuclease

Cas9 nuclease for the generation of double-strand breaks in CRISPR-Cas9 genome editing
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ArciTect™ Cas9-eGFP Nuclease

Enhanced green fluorescent protein (eGFP)-tagged Cas9 nuclease for the generation of double-strand breaks in CRISPR-Cas9 genome editing
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ArciTect™ Cas9 Nickase

Modified Cas9 nuclease for the generation of single-strand breaks in CRISPR-Cas9 genome editing