Genome Editing
The use of genome editing tools to generate specific changes to the DNA sequence of human pluripotent stem cells (hPSCs), by either introducing or correcting mutations, provides more accurate modeling of human disease when the gene-edited hPSCs are subsequently differentiated into human-derived tissues.
Products
Cultureware and General Supplies 4 (2)
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Costar® Microcentrifuge Tubes
Non-sterile, clear, polypropylene snap-cap microcentifuge tubes -
Axygen® Thin-Wall PCR Tubes
Non-sterile, clear, RNase/DNase-free, polypropylene conical tubes with caps
Small Molecules 4 (7)
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KU0060648
NHEJ pathway inhibitor; Inhibits DNA-dependent protein kinase (DNA-PK) -
Nocodazole
Microtubule polymerization inhibitor; Inhibits beta-tubulin -
NU7441
NHEJ pathway inhibitor; Inhibits DNA-dependent protein kinase (DNA-PK) -
RS-1
HDR pathway enhancer; Enhances RAD51
