Anti-Human CD34 Antibody, Clone 8G12

Mouse monoclonal IgG1 antibody against human CD34

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From: 859 USD

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Mouse monoclonal IgG1 antibody against human CD34
From: 859 USD

Overview

CD34 is an ~105 - 120 kDa type 1 transmembrane glycoprotein expressed on the surface of most human hematopoietic stem and progenitor cells (HSPCs), as well as on endothelial cells and some tumor cell lines. The frequency of CD34+ cells is low in bone marrow (1 - 4%), cord blood (~1%), and peripheral blood (< 0.1%). CD34 is used to identify and isolate HSPCs, including those capable of reconstituting hematopoiesis after transplantation. Distinct epitope groups have been assigned to CD34 based on differences in the structure of carbohydrate groups, which affects their sensitivity to enzymatic cleavage. The 8G12 antibody recognizes a class III epitope (resistant to neuraminidase and O-glycoprotease). Clone 8G12 does not recognize rhesus macaque CD34.
Subtype:
Primary Antibodies
Target Antigen:
CD34
Reactive Species:
Human
Conjugation:
APC; FITC; PE
Host Species:
Mouse
Cell Type:
Hematopoietic Stem and Progenitor Cells
Application:
Cell Isolation; Flow Cytometry
Area of Interest:
Stem Cell Biology

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STEMCELL TECHNOLOGIES INC.’S QUALITY MANAGEMENT SYSTEM IS CERTIFIED TO ISO 13485. PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED.