Hematopoietic Stem and Progenitor Cell Research

A multipotent hematopoietic stem cell (HSC) is defined by the properties of self-renewal and differentiation into all of the different types of mature blood cells. See MoreAs HSCs divide, they progress through a series of lineage commitment steps, producing hematopoietic progenitor cells (HPCs) that are shorter lived and more restricted in their differentiation potential.

Whether you’re uncovering the mysteries of HSC biology, developing new cell therapies or manipulating cells with CRISPR-Cas9, the culture conditions you choose can make a difference in your experiments. Our serum-free media and premixed cytokine supplements provide optimized, highly reproducible culture conditions for your research.

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Brochure Small Molecules for HSPC Expansion: UM171 and UM729
Brochure StemSpan™ CD34+ Expansion Supplement
Brochure StemSpan™ Myeloid Expansion Supplement
Brochure StemSpan™ Erythroid Expansion Supplement
Brochure StemSpan™ Megakaryocyte Expansion Supplement

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Products

Cell Culture Media and Supplements 4 (28)

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StemSpan™ NK Cell Generation Kit

For expansion and differentiation of human CD34+ hematopoietic progenitor cells to NK cells
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StemSpan™ NK Cell Differentiation Supplement (100X)

Supplement for the differentiation of lymphoid progenitors to NK cells
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StemSpan™ T Cell Progenitor Maturation Supplement (10X)

Supplement for the maturation of lymphoid progenitor cells to T cells
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StemSpan™ Lymphoid Differentiation Coating Material (100X)

Coating material for the expansion and differentiation of lymphoid cells

Small Molecules 4 (15)

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OAC1

Inducer of OCT4 expression
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16,16-Dimethyl Prostaglandin E2

Prostanoid pathway activator; Inhibits 15-hydroxy PGDH
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UM729

Pyrimido-indole derivative that enhances HSC self-renewal in vitro
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Valproic Acid (Sodium Salt)

Epigenetic modifier; Inhibits histone deacetylase (HDAC)1

Cytokines and Proteins 4 (99)

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Human Recombinant TGF-beta 1 (Cell Culture Ready)

Ready-to-use transforming growth factor beta 1
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Human Recombinant PDGF-DD

Platelet-derived growth factor DD
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Human Recombinant IL-2 (E. coli-expressed)

Interleukin 2
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Human Recombinant IL-15, ACF

Interleukin 15, animal component-free

Cultureware and General Supplies 4 (5)

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Corning® 245 mm Square Dish, Non-Treated

Square dish without handles
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Corning® Disposable Erlenmeyer Flask, 500 mL

Sterile polycarbonate baffled Erlenmeyer flask
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Falcon® 96-Well Flat-Bottom Microplate, Tissue Culture-Treated

Clear polystyrene, flat-bottom, tissue culture-treated multiwell plate with lid
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Falcon® 24-Well Flat-Bottom Plate, Tissue Culture-Treated

Clear polystyrene flat-bottom, tissue culture-treated multiwell plate with lid

Buffers and Solutions 4 (4)

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Dulbecco's Phosphate Buffered Saline with 2% Fetal Bovine Serum

Cell culture buffer
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HBSS, Modified (Without Ca++ and Mg++)

Hanks' Balanced Salt Solution (HBSS) without calcium and magnesium
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HBSS with 10 mM HEPES, Without Phenol Red

Hanks' Balanced Salt Solution (HBSS) modified with 10 mM HEPES, without phenol red
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D-PBS (Without Ca++ and Mg++)

Dulbecco’s phosphate-buffered saline without calcium and magnesium

Laboratory Equipment 4 (1)

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Hausser Scientific™ Bright-Line Hemocytometer

Counting chamber with 2 cover glasses

Training and Education 4 (1)

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Pluripotent Stem Cell Training

Training to support the culture of hPSCs and their differentiation towards cerebral organoids, intestinal organoids, cardiomyocytes, or hematopoietic progenitors

Cell Engineering and Molecular Tools 4 (1)

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ArciTect™ Human CRISPR Optimization Kit

Complete kit for optimization of genome editing in human cells

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