Indomethacin
Inhibits COX-1 and COX-2
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Overview
DIFFERENTIATION
· Activates peroxisome proliferator-activated receptor-γ (PPARγ), a ligand-activated transcription factor known to play a pivotal role in adipogenesis (Lehmann et al.).
· Inhibits chondrogenic differentiation in ATDC5 cells and bone marrow stem cells (Caron et al.).
CANCER RESEARCH
· Inhibits growth of mouse mammary tumors (Fulton).
· Induces apoptosis in prostate and gastric cancer cells (Chiou et al.; Liu et al.).
Protocols and Documentation
Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.
Applications
This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.
Resources and Publications
Educational Materials (3)
Related Products
Quality Statement:
PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED. FOR ADDITIONAL INFORMATION ON QUALITY AT STEMCELL, REFER TO WWW.STEMCELL.COM/COMPLIANCE.
