Anti-Human CD34 Antibody, Clone 8G12

Mouse monoclonal IgG1 antibody against human CD34

Anti-Human CD34 Antibody, Clone 8G12

Mouse monoclonal IgG1 antibody against human CD34

From: 1,198 USD
Catalog #
(Select a product)
Mouse monoclonal IgG1 antibody against human CD34
Add to Wish List

Overview

CD34 is an ~105 - 120 kDa type 1 transmembrane glycoprotein expressed on the surface of most human hematopoietic stem and progenitor cells (HSPCs), as well as on endothelial cells and some tumor cell lines. The frequency of CD34+ cells is low in bone marrow (1 - 4%), cord blood (~1%), and peripheral blood (< 0.1%). CD34 is used to identify and isolate HSPCs, including those capable of reconstituting hematopoiesis after transplantation. Distinct epitope groups have been assigned to CD34 based on differences in the structure of carbohydrate groups, which affects their sensitivity to enzymatic cleavage. The 8G12 antibody recognizes a class III epitope (resistant to neuraminidase and O-glycoprotease). Clone 8G12 does not recognize rhesus macaque CD34.
Subtype
Primary Antibodies
Target Antigen
CD34
Reactive Species
Human
Conjugation
APC, FITC, PE
Host Species
Mouse
Cell Type
Hematopoietic Stem and Progenitor Cells
Species
Human
Application
Cell Isolation, Flow Cytometry
Area of Interest
Stem Cell Biology

Protocols and Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type
Product Name
Catalog #
Lot #
Language
Catalog #
60121AZ
Lot #
All
Language
English
Catalog #
60121PE
Lot #
All
Language
English
Catalog #
60121FI
Lot #
All
Language
English
Document Type
Safety Data Sheet
Catalog #
60121AZ
Lot #
All
Language
English
Document Type
Safety Data Sheet
Catalog #
60121PE
Lot #
All
Language
English
Document Type
Safety Data Sheet
Catalog #
60121FI
Lot #
All
Language
English

Applications

This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.

Resources and Publications

Educational Materials (1)