· Maintains the bi-potent, quiescent state in hepatic stellate cells of Wistar rats (Kordes et al.).
· Induces differentiation of mouse embryonal carcinoma and embryonic stem cells to neurons (Ding et al.).
· Induces production of T memory stem cell-like (T-SCM) cells from mouse or human CD8+ T cells with evidence of increased persistence, proliferation, and anti-tumor activity after adoptive transfer of mouse-derived T-SCM (Forget et al.; Gattinoni et al.).
· Inhibits cell proliferation and induces apoptosis in human alveolar rhabdomyosarcoma cells (Zeng et al.).
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