Hedgehog pathway inhibitor; Inhibits Smoothened (SMO)
· Reduces proliferation of rat neural progenitor cells and mouse neurospheres (Lai et al.; Palma and Ruiz i Altaba).
· Reduces proliferation of mouse mammospheres (Liu et al.).
· Promotes differentiation of pancreatic cells from human embryonic stem cells (D'Amour et al.).
· Inhibits the growth of human and mouse medulloblastoma cells, and human glioblastoma cells (Bar et al., Berman et al.).
Protocols and Documentation
Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.
This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.
Resources and Publications
Educational Materials (4)
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PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED. FOR ADDITIONAL INFORMATION ON QUALITY AT STEMCELL, REFER TO WWW.STEMCELL.COM/COMPLIANCE.