Rosiglitazone
PPARγ activator
Overview
MAINTENANCE AND SELF-RENEWAL
· Stimulates embryonic mouse neural stem cell proliferation and inhibits neuronal differentiation (Wada et al.).
DIFFERENTIATION
· Induces adipocyte differentiation in C3H10T1/2 stem cells (Lehmann et al.).
· Promotes endothelial differentiation, and inhibits smooth muscle differentiation, in angiogenic progenitor cells (Wang et al.).
· Stimulates adipocyte differentiation, and decreases osteogenesis, in mouse and human bone marrow-derived mesenchymal stem cells (Ali et al.; Benvenuti et al.; Lecka-Czernik et al.; Sorocéanu et al.).
· Enhances osteoclast formation in mouse bone marrow cells stimulated with RANKL and M-CSF (Wu et al.).
Scientific Resources
Product Documentation
Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.
Educational Materials (1)
Product Applications
This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.
Data and Publications
Publications (8)
Abstract
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Quality Statement:
PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED. FOR ADDITIONAL INFORMATION ON QUALITY AT STEMCELL, REFER TO WWW.STEMCELL.COM/COMPLIANCE.