Gene Edit Liver Organoids - CRISPR-Cas9 Genome Editing

Genome Editing

Genome Editing of Liver Organoids

Liver organoids are miniature three-dimensional (3D) cell culture systems that serve as a valuable model for studying liver biology. A key benefit of liver organoids is that they are amenable to genome editing, such as by CRISPR-Cas9, an RNA-guided genome editing technology that is revolutionizing cell biology with its ease and efficiency. Explore our protocol for information on how to perform high-efficiency CRISPR-Cas9 genome editing of liver organoids to develop better in vitro disease models and study organ development.