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Hematopoietic Stem and Progenitor Cells

Genome Editing

Genome Editing of Hematopoietic Stem and Progenitor Cells

CRISPR-Cas9 genome editing of human hematopoietic stem and progenitor cells (HSPCs) has advanced our understanding of the mechanisms that regulate hematopoiesis and is contributing to the development of novel cellular therapies. However, genome editing of HSPCs can be challenging due to inefficient delivery and expression of the CRISPR-Cas9 components. Explore the protocols and resources below for support on how to perform high-efficiency genome editing of HSPCs in your own lab.

Technical Bulletin Genome Editing of Human CD34+ Hematopoietic Stem and Progenitor Cells Using the ArciTect™ CRISPR-Cas9 System and StemSpan™ Media
Technical Bulletin Evaluation of Genome Editing
Webinar CRISPR-Cas9 Editing of Hematopoietic Stem and Progenitor Cells
Technical Bulletin Genome Editing with Direct Cas9 RNP Delivery Design Considerations
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  1. Technical Bulletin 3 items
  2. Webinar 1 item
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  1. Cell Culture Media and Supplements 1 item
  2. Cell Engineering and Molecular Tools 3 items
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Area of Interest
  1. Cell Therapy Research 2 items
  2. Disease Modeling 3 items
  3. Drug Discovery and Toxicity Testing 1 item
  4. Stem Cell Biology 3 items
  5. Transplantation Research 1 item
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  1. ArciTect 3 items
  2. EasySep 1 item
  3. MethoCult 1 item
  4. StemSpan 2 items
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  1. Erythroid Cells 1 item
  2. Hematopoietic Stem and Progenitor Cells 2 items
  3. Pluripotent Stem Cells 2 items
  4. Red Blood Cells 1 item
  5. T Cells 2 items
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Product Information Sheets

For detailed protocols developed specifically for our products, please consult the Product Information Sheet or enter the product keyword or catalog number below.


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