Pluripotent Stem Cells

Genome Editing

Genome Editing of hPSCs

CRISPR-Cas9 genome editing of human pluripotent stem cells (hPSCs) has enabled researchers to generate better disease models, for example by creating specific mutations of interest prior to differentiating to the disease-relevant cell type. However, genome editing hPSCs can be challenging. Explore optimized protocols and resources on how to perform high-efficiency knockout and knock-in genome editing in hPSCs in your own lab.