Intestinal Organoids

Genome Editing

Genome Editing of Intestinal Organoids

Organoids are helping scientists push the boundaries for in vitro study of the intestinal epithelium. A key benefit of intestinal organoid cultures is that they are amenable to genome editing, such as by CRISPR-Cas9, an RNA-guided technology that has revolutionized genome editing due to its ease and efficiency. Explore our protocols and resources for information on how to perform high-efficiency CRISPR-Cas9 genome editing of intestinal organoids to develop better in vitro disease models and study organ development.

Technical Bulletin Evaluation of Genome Editing

Technical Bulletin Genome Editing with Direct Cas9 RNP Delivery Design Considerations

Protocol CRISPR-Cas9 Genome Editing of Human Intestinal Organoids

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