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Immune Cells

Genome Editing

Genome Editing of Immune Cells

CRISPR-Cas9 genome editing of immune cell types holds great therapeutic potential, but application of genome editing to primary human immune cells has been hampered by challenges in efficient delivery and expression of the CRISPR machinery. Explore our protocols and resources for information on how to overcome these barriers and perform high-efficiency genome editing of these difficult-to-manipulate cell types in your own lab.

Technical Bulletin Genome Editing of Human Primary T Cells Using CRISPR-Cas9
Technical Bulletin Evaluation of Genome Editing
Technical Bulletin Genome Editing with Direct Cas9 RNP Delivery Design Considerations
Video CAR T Cell Manufacturing Workflow: Isolation, Activation and Expansion
Tech Tip Acquiring DNA or RNA from Positively Selected Cells
Protocol CRISPR-Cas9 Genome Editing of Human NK Cells
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  1. Protocol 1 item
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  1. Cell Engineering and Molecular Tools 4 items
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Area of Interest
  1. Cell Line Development 1 item
  2. Cell Therapy Research 5 items
  3. Disease Modeling 4 items
  4. Immunology 1 item
  5. Stem Cell Biology 1 item
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  1. ArciTect 4 items
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  3. ImmunoCult 3 items
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  1. Hematopoietic Stem and Progenitor Cells 1 item
  2. NK Cells 1 item
  3. Pluripotent Stem Cells 2 items
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  5. T Cells, CD4+ 1 item
  6. T Cells, CD8+ 1 item
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Product Information Sheets

For detailed protocols developed specifically for our products, please consult the Product Information Sheet or enter the product keyword or catalog number below.


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