Directed Differentiation and Disease Modeling
Human pluripotent stem cell (hPSC)-based models hold tremendous potential for the study of human development and disease. hPSC-derived cells provide a physiologically relevant model for drug discovery, cell therapy validation and disease research.
Explore the resources below to support your disease modeling studies using hPSCs.
Highly Efficient Single-Cell Human Pluripotent Stem Cell Cloning and Robust Cardiomyocyte Differentiation
Recorded during the ISSCR 2017 Innovation Showcase in Boston, this tutorial highlights human pluripotent stem cell (hPSC) gene-editing and cardiac differentiation workflows using the CloneR™ supplement and the STEMdiff™ Cardiomyocyte System. This talk is presented by STEMCELL Technologies’ Dr. Adam Hirst, scientist for pluripotent stem cell biology, and Dr. Vincenzo Macri, senior scientist for cardiomyocyte stem cell biology.
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Panel: Challenges in Ensuring hPSC Quality
Hear global experts discuss key issues impacting the use of human pluripotent stem cells in this series of webinars provided in partnership with Nature Research.
Introduction to Pluripotent Stem Cells
Get an overview on in vitro hPSC culture and derivation for research use, as well as insights into the role of hPSCs for clinical applications such as drug development and cell therapy.
Quality Control for Pluripotent Stem Cells
Get to know the key quality attributes of hPSC cultures, including techniques for maintaining and assessing genomic integrity, pluripotency, and morphology.
Assessing Pluripotency
High-quality hPSCs should maintain the potential to differentiate into progenitors of all three germ lineages. Learn about pluripotency and optimized assays for in vitro validation.