Epigenetic modifier; Inhibits histone deacetylase (HDAC)1 and HDAC6
· Increases the reprogramming efficiency of mouse embryonic fibroblasts to induced pluripotent stem (iPS) cells (Huangfu et al.).
· Resets epigenetic memory in mouse iPS cells, in combination with 5-Azacytidine (Kim et al.).
·Increases the efficiency of cloned mouse embryo development by somatic cell nuclear transfer (Kishigami et al.).
MAINTENANCE AND SELF-RENEWAL
· Prevents dedifferentiation of primary rat hepatocytes in culture, maintaining liver-specific cellular functions (Henkens et al.).
· Promotes differentiation of hepatocytes from human mesenchymal stem cells (Snykers et al.).
Protocols and Documentation
Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.
This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.
Resources and Publications
Educational Materials (3)
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PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED. FOR ADDITIONAL INFORMATION ON QUALITY AT STEMCELL, REFER TO WWW.STEMCELL.COM/COMPLIANCE.