Hedgehog pathway activator; Activates Smoothened (SMO)
· Improves neuronal differentiation of human induced pluripotent stem cells (Mak et al.).
· Induces proliferation and survival of neuronal and glial precursors in vitro and in vivo (Bragina et al.).
· Prevents glucocorticoid neurotoxicity in Math1-Cre, SmoM2 transgenic mice (Heine et al.).
· Rescues cerebellar size and behavioral phenotypes in the Ts65Dn mouse model of Down Syndrome (Das et al.).
Protocols and Documentation
Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.
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Resources and Publications
Educational Materials (2)
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