Collagenase Type III

For digestion of native collagen fibrils

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From: 74 USD

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For digestion of native collagen fibrils
From: 74 USD

Overview

Collagenase is a protease consisting of a single polypeptide chain approximately 1,000 amino acid residues in length. Collagenase is capable of digesting native collagen fibrils commonly found in connective tissues and therefore is frequently used for tissue dissociation. Collagenase preparations contain the activity of several proteases, including collagenase, caseinase, clostripain, and trypsin (Kessler & Yaron). Collagenase Type III contains low levels of proteolytic activity, especially for caseinase, clostripain, and trypsin. Collagenase Type III has been used for the digestion of mammary glands (Rønnov-Jessen et al.), colon cancer stem cells (Prince et al.), and breast epithelial tumor cells (Chan et al.).
Subtype:
Enzymatic
Alternative Names:
Clostridium histolyticum collagenase; Collagenase 3; Collagenase Type 3; Collagenase III
Cell Type:
Cancer Cells and Cell Lines; Dendritic Cells; Endothelial Cells; Mammary Cells; T Cells, CD4+
Species:
Human; Mouse; Rat; Non-Human Primate; Other
Area of Interest:
Cancer Research; Endothelial Cell Biology; Epithelial Cell Biology; Immunology; Stem Cell Biology
Molecular Weight:
68 - 130 kDa

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This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.

STEMCELL TECHNOLOGIES INC.’S QUALITY MANAGEMENT SYSTEM IS CERTIFIED TO ISO 13485. PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED.