Epigenetic modifier; Inhibits DNA methyltransferase (DNMT)
· Increases reprogramming efficiency of mouse fibroblasts to induced pluripotent stem (iPS) cells by inducing full reprogramming of partially reprogrammed cells (Mikkelsen et al.).
· Resets epigenetic memory in mouse iPS cells, in combination with Trichostatin A (Kim et al.).
· Enhances differentiation to cardiomyocytes from human embryonic stem cells (Yoon et al.).
· Wide range of anti-metabolic activities when tested against cultured cancer cells and an effective chemotherapeutic agent for acute myelogenous leukemia
Protocols and Documentation
Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.
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Resources and Publications
Educational Materials (3)
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