1-Azakenpaullone

Inhibits glycogen synthase kinase 3β (GSK3β)

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1-Azakenpaullone

Inhibits glycogen synthase kinase 3β (GSK3β)

5 mg
Catalog #74252
449 USD

Overview

1-Azakenpaullone is a potent and highly selective inhibitor of glycogen synthase kinase 3β (IC₅₀ = 18 nM) and is highly preferential to GSK3β versus other cyclin-dependent kinases (CDKs) including CDK/cyclin B and CDK5/p25 (IC₅₀ = 2 µM and 4.2 µM, respectively; Kunick et al.).


MAINTENANCE AND SELF-RENEWAL
· In combination with ID-8 (Catalog #72502) and FK506 (Catalog #74152), supports human pluripotent stem cells in long-term propagation, maintaining pluripotency, and capacity to differentiate (Yasuda et al.).
Alternative Names:
Not applicable
CAS Number:
676596-65-9
Chemical Formula:
C₁₅H₁₀BrN₃O
Molecular Weight:
328.2 g/mol
Purity:
≥ 98%
Target:
GSK3β

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This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.

STEMCELL TECHNOLOGIES INC.’S QUALITY MANAGEMENT SYSTEM IS CERTIFIED TO ISO 13485. PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED.