Hedgehog pathway activator; Activates Smoothened (SMO)
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· Improves neuronal differentiation of human induced pluripotent stem cells (Mak et al.).
· Induces proliferation and survival of neuronal and glial precursors in vitro and in vivo (Bragina et al.).
· Prevents glucocorticoid neurotoxicity in Math1-Cre, SmoM2 transgenic mice (Heine et al.).
· Rescues cerebellar size and behavioral phenotypes in the Ts65Dn mouse model of Down Syndrome (Das et al.).
Protocols and Documentation
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Resources and Publications
Educational Materials (2)
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