Collagenase Type IV

For digestion of native collagen fibrils

Collagenase Type IV

For digestion of native collagen fibrils

From: 103 USD
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For digestion of native collagen fibrils
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Product Advantages


  • Maintain receptor integrity with a collagenase preparation low in tryptic activity

  • Dissociate pancreatic islet cells effectively

Overview

Digest native collagen fibrils in connective tissues with Collagenase Type IV, sourced from Clostridium histolyticum. Collagenase preparations typically contain the activity of several proteases, including collagenase, caseinase, clostripain, and trypsin (Kessler & Yaron). Frequently used to dissociate pancreatic islets (Taguchi et al.), and in applications where maintenance of receptor integrity is required, Collagenase Type IV has low tryptic activity compared to other collagenase preparations.
Subtype
Enzymatic
Alternative Names
Clostridium histolyticum collagenase; Collagenase 4; Collagenase Type 4; Collagenase IV
Cell Type
Cardiomyocytes, PSC-Derived, Epithelial Cells, Mammary Cells, Mesenchymal Stromal Cells
Species
Human, Mouse, Non-Human Primate, Other, Rat
Application
Cell Culture
Area of Interest
Cancer, Endothelial Cell Biology, Epithelial Cell Biology, Immunology, Neuroscience, Stem Cell Biology
Molecular Weight
68 - 130 kDa

Protocols and Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type
Product Name
Catalog #
Lot #
Language
Catalog #
07426, 100-0680, 07427
Lot #
All
Language
English
Document Type
Safety Data Sheet
Catalog #
07426, 100-0680, 07427
Lot #
All
Language
English

Applications

This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.

Resources and Publications

Educational Materials (1)