Due to the difficulty of obtaining human brain tissue for experimental studies, rodents have traditionally been popular model organisms for neurological disease modeling. In recent years, however, researchers have begun using induced pluripotent stem cells (iPSCs) to generate more representative models for studying human neurological disease. These iPSC-based models, including iPSC derived neurons, hold tremendous potential for the study of human neurological disease. Researchers can now generate patient-specific differentiated cell types, bridging the gap between studies using animal models and clinical research.
We’ve created these resources to help you with your research in neurological disease modeling, and to give you a taste of what others are doing in the field.
In this webinar, Dr. Andrew Tidball discusses current and potential uses of iPS cells for modeling epilepsies, how to develop different iPS cell-based model systems, as well as the key advantages and drawbacks of using these model systems.View Now >
Learn the techniques and protocols to derive and maintain hPSCs from somatic cells and how to differentiate them towards specialized cell types.