Neurological Disease Modeling

Due to the difficulty of obtaining human brain tissue for experimental studies, rodents have traditionally been popular model organisms for neurological disease modeling. In recent years, however, researchers have begun using induced pluripotent stem cells (iPSCs) to generate more representative models for studying human neurological disease. These iPSC-based models, including iPSC derived neurons, hold tremendous potential for the study of human neurological disease. Researchers can now generate patient-specific differentiated cell types, bridging the gap between studies using animal models and clinical research.

We’ve created these resources to help you with your research in neurological disease modeling, and to give you a taste of what others are doing in the field.

Overview of brain organogenesis and the applications of brain organoids in studying the development and maturation of the nervous system
Overview of the key concepts and mechanisms in glioblastoma multiforme biology
Details on human iPSC-derived models of neuropsychiatric and neurodegenerative disorders
Overview of the types of NSCs and their potential use as therapeutic agents for disease

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