JNK pathway inhibitor; Inhibits JNK1, JNK2 and JNK3
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· Direct lineage reprogramming of fibroblasts to mature neurons, in combination with CHIR99021, RepSox, Forskolin, Gö6983, Valproic Acid and Y-27632 (Hu et al.).
· Inhibits BMP9-induced osteogenic differentiation in cultured mouse mesenchymal stem cells (MSCs) and in primary bone marrow stromal cells (Zhao et al.).
· Promotes adipogenic, but represses osteogenic differentiation of human MSCs (Bilkovski et al.; Liu et al.; Qiu et al.; Tominaga et al.).
· Causes cell death and inhibits neurogenesis when added during early stages of neuronal culture (Tiwari et al.).
Protocols and Documentation
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Resources and Publications
Educational Materials (2)
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