Anti-Human CD298 Antibody, Clone LNH-94

Mouse monoclonal IgG1 antibody against human CD298

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From: 400 USD

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Mouse monoclonal IgG1 antibody against human CD298
From: 400 USD

Overview

The LNH-94 antibody reacts with human CD298, the β3 subunit of the Na+/K+ ATPase. The Na+/K+ ATPase is a 42 kDa type II transmembrane protein composed of four catalytic α subunits and three smaller glycosylated non-catalytic β subunits. The Na+/K+ ATPase is important for establishing electrochemical gradients and maintaining normal resting membrane potential by coupling ATP hydrolysis to the active transport of Na+ and K+. The β subunits have been reported to act as chaperones that stabilize the α subunits and occlude K+. CD298 has been used to identify metastatic human cancer cells in mouse xenograft models and has been reported to modulate aspects of immunity, including HIV production, and T cell and B cell activation. CD298 is found on leukocytes, platelets, and most other tissue types.
Subtype:
Primary Antibodies
Target Antigen:
CD298
Reactive Species:
Human
Conjugation:
PE; APC
Host Species:
Mouse
Cell Type:
Granulocytes and Subsets; Monocytes; T Cells; Lymphocytes; Mammary Cells; B Cells
Application:
Flow Cytometry
Area of Interest:
Immunology; Transplantation Research; Endothelial Cell Biology; Disease Modeling; Cancer Research

Scientific Resources

Educational Materials

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Product Applications

This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.

Data and Publications

Data

Flow cytometry analysis of human peripheral blood mononuclear cells (PBMCs; gated on lymphocytes) labeled with Anti-Human CD298 Antibody, Clone LNH-94, PE (filled histogram), or Mouse IgG1, kappa Isotype Control Antibody, Clone MOPC-21, PE (Catalog #60070PE; solid line histogram).

Flow cytometry analysis of human peripheral blood mononuclear cells (PBMCs; gated on lymphocytes) labeled with Anti-Human CD298 Antibody, Clone LNH-94, APC (filled histogram), or Mouse IgG1, kappa Isotype Control Antibody, Clone MOPC-21, APC (Catalog # 60070AZ; solid line histogram).

STEMCELL TECHNOLOGIES INC.’S QUALITY MANAGEMENT SYSTEM IS CERTIFIED TO ISO 13485. PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED.