Start your autoimmune disease research confidently with a reliable supply of ethically sourced, peripheral blood (PB) products from donors diagnosed with lupus. Lupus is an autoimmune disorder that occurs when the body's immune system attacks its own tissues and organs, resulting in widespread inflammation and tissue damage. Cells from donors with lupus can be used to model physiological mechanisms. Product options include half or full fresh leukopaks and frozen mononuclear cells (MNCs or PBMCs). We help you get the cells you need with personalized service and flexible delivery times.

Leukopaks are an enriched leukapheresis product consisting of a large number of single-donor MNCs. Each full-sized leukopak is produced from ~2 - 3x blood volumes using the Spectra Optia® Apheresis System, with acid-citrate-dextrose solution A (ACDA) as the anticoagulant. Primary human MNCs are isolated from peripheral blood, leukapheresis, or whole blood samples using density gradient separation or red blood cell lysis and cryopreserved in animal component-free CryoStor®CS10 medium (Catalog #07930). All PB products are obtained from donors diagnosed with lupus using Institutional Review Board (IRB)-approved consent forms and protocols. Additional documentation and high-resolution HLA typing (Class I and Class II alleles) may be available upon request. Donor specifications (e.g. BMI category, age, ethnicity, etc.) can be requested in the comment box above, after selecting from the product options. Donors are screened for HIV-1, HIV-2, hepatitis B, and hepatitis C.

Certain products are only available in select territories. Please contact your local sales representative or Product & Scientific Support at techsupport@stemcell.com for further information.

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