T Cell Engineering

Activation of T cells is required for efficient transduction of cells with foreign genetic material, such as vectors expressing chimeric antigen receptors (CARs) or modified­ T cell receptors (TCRs). See MoreThe reprogrammed T cells can then be expanded for further analysis, cryopreservation, and possible infusion.

To stimulate T cells, choose from our ImmunoCult™ Human T Cell Activators, reagents designed to activate human T cells in the absence of magnetic beads, feeder cells, or antigen. Once activated, T cells can be cultured and expanded in our optimized serum- and xeno-free ImmunoCult™-XF T Cell Expansion Medium.

High yields of T cells can also be obtained by differentiating human pluripotent stem cells (hPSCs) to T cells using STEMdiff™ T Cell Kit.