(±)-Flurbiprofen

PI3K/AKT pathway inhibitor; Inhibits COX-1 and COX-2

(±)-Flurbiprofen

PI3K/AKT pathway inhibitor; Inhibits COX-1 and COX-2

From: 459 USD
Catalog #
73922_C
PI3K/AKT pathway inhibitor; Inhibits COX-1 and COX-2

Overview

(±)-Flurbiprofen is a cell-permeable and non-steroidal anti-inflammatory agent. It is a potent non-selective inhibitor of cyclooxygenase (COX) with EC50 = 0.1 and 0.4 µM for the inhibition of recombinant human COX-1 and COX-2, respectively (Gierse et al.).

MAINTENANCE AND SELF-RENEWAL
· Maintains self-renewal and pluripotency in hESC cells grown in conditions that induce differentiation (Bhanu et al.; Desbordes et al.).

CANCER RESEARCH
· Inhibits tumor growth in models of prostate cancer, familial adenomatous polyposis, and brain cancer (King, Jr & Khalili; Grubbs et al.; Wechter et al.; Zemskova et al.).
Alternative Names
Ansaid
Cell Type
Brain Tumor Stem Cells, Cancer Cells and Cell Lines, Prostate Cells
Species
Human, Mouse, Rat, Non-Human Primate, Other
Application
Maintenance
Area of Interest
Cancer, Disease Modeling, Neuroscience
CAS Number
5104-49-4
Chemical Formula
C₁₅H₁₃FO
"
Molecular Weight
244.3 g/mol
Purity
≥ 99%
Pathway
PI3K/AKT
Target
COX-1

Protocols and Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type
Product Name
Catalog #
Lot #
Language
Product Name
(±)-Flurbiprofen
Catalog #
73924
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
(±)-Flurbiprofen
Catalog #
73924
Lot #
All
Language
English

Applications

This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.

Contact STEMCELL Technologies

Our Customer Service, Sales, and Product and Scientific Support departments in North America are available between 6 am and 5 pm Pacific Time (9 am and 8 pm Eastern Time). One of our representatives will be happy to help you by telephone or email. Please complete the form to contact us by email. A representative will get back to you shortly.
  •  

StemCell Technologies Inc. and affiliates ("STEMCELL Technologies") does not share your email address with third parties. StemCell Technologies Inc. will use your email address to confirm your identity and send you newsletters, transaction-related emails, promotional and customer service emails in accordance with our privacy policy. You can change your email preferences at any time.