MAINTENANCE AND SELF-RENEWAL
· Maintains self-renewal and pluripotency in hESC cells grown in conditions that induce differentiation (Bhanu et al.; Desbordes et al.).
· Inhibits tumor growth in models of prostate cancer, familial adenomatous polyposis, and brain cancer (King, Jr & Khalili; Grubbs et al.; Wechter et al.; Zemskova et al.).
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