(±)-Flurbiprofen

PI3K/AKT pathway inhibitor; Inhibits COX-1 and COX-2

More Views

From: 95 USD

Options

* Required Fields

Catalog # (Select a product)
PI3K/AKT pathway inhibitor; Inhibits COX-1 and COX-2
From: 95 USD

Overview

(±)-Flurbiprofen is a cell-permeable and non-steroidal anti-inflammatory agent. It is a potent non-selective inhibitor of cyclooxygenase (COX) with EC50 = 0.1 and 0.4 µM for the inhibition of recombinant human COX-1 and COX-2, respectively (Gierse et al.).

MAINTENANCE AND SELF-RENEWAL
· Maintains self-renewal and pluripotency in hESC cells grown in conditions that induce differentiation (Bhanu et al.; Desbordes et al.).

CANCER RESEARCH
· Inhibits tumor growth in models of prostate cancer, familial adenomatous polyposis, and brain cancer (King, Jr & Khalili; Grubbs et al.; Wechter et al.; Zemskova et al.).
Alternative Names:
Ansaid
CAS Number:
5104-49-4
Chemical Formula:
C₁₅H₁₃FO
"
Molecular Weight:
244.3 g/mol
Purity:
≥ 99%
Pathway:
PI3K/AKT
Target:
COX-1

Scientific Resources

Product Documentation

Document Type
Product Name
Catalog #
Lot #
Language

Educational Materials

(5)

Product Applications

This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.

STEMCELL TECHNOLOGIES INC.’S QUALITY MANAGEMENT SYSTEM IS CERTIFIED TO ISO 13485. PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED.