Myeloid Cell Research

Blood cells of the myeloid lineage arise from a population of restricted progenitor cells referred to as common myeloid progenitors (CMPs). See MoreCMPs are derived from hematopoietic stem cells (HSCs) and are located in adult bone marrow. Myeloid cells include macrophages, erythroid cells, megakaryocytes, a subset of dendritic cells (DCs), monocytes, neutrophils, eosinophils and basophils. These cell types may be isolated from fresh^1,2 or frozen² tissues including fresh peripheral blood. Myeloid progenitor cells may also be generated through differentiation of human CD34+ cells in serum-free media with the addition of specific cytokine cocktails to produce megakaryocyte, erythroid or myeloid progenitors.