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Dibutyryl-cAMP

cAMP pathway activator; Activates cAMP-dependent protein kinases

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Dibutyryl-cAMP

cAMP pathway activator; Activates cAMP-dependent protein kinases

From: 75 USD
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cAMP pathway activator; Activates cAMP-dependent protein kinases
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Overview

Dibutyryl-cAMP is a cell-permeable cyclic AMP (cAMP) analog that activates cAMP-dependent protein kinases (Schwede et al.). This product is supplied as the sodium salt of the molecule.


DIFFERENTIATION
· Suppresses experimental autoimmune encephalomyelitis development by reducing demyelination and mobilizing neural stem cells in the subventricular zone towards the demyelinated plaques (Khezri et al.).

· Induces intrinsic axon growth in peripheral and central nervous systems, and morphological differentiation of astrocytes (Knott et al.; Imamura & Ozawa).

· Stimulates neurite outgrowth in PC12 cells (Maruoka et al.).
Alternative Names

Bucladesine; DC 2797

Cell Type
Astrocytes, Neural Cells, PSC-Derived, Neurons
Species
Human, Mouse, Non-Human Primate, Other, Rat
Application
Differentiation, Expansion
Area of Interest
Disease Modeling, Neuroscience
CAS Number
16980-89-5
Chemical Formula
C₁₈H₂₃N₅O₈P · Na
Molecular Weight
491.4 g/mol
Purity
≥ 95%
Pathway
cAMP
Target
cAMP-Dependent Kinase

Protocols and Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type
Product Name
Catalog #
Lot #
Language
Document Type
Product Information Sheet
Product Name
Dibutyryl-cAMP
Catalog #
73886, 73882, 73884, 100-0244
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
Dibutyryl-cAMP
Catalog #
73886, 73882, 73884
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
Dibutyryl-cAMP
Catalog #
100-0244
Lot #
All
Language
English

Applications

This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.

Research Area
Workflow Stages

Resources and Publications

Educational Materials (3)

Cytokines, Chemokines and Growth Factors
Brochure
Cytokines, Chemokines and Growth Factors
Small Molecules, Big Impact in Pluripotent Stem Cell Research
Wallchart
Small Molecules, Big Impact in Pluripotent Stem Cell Research
Small Molecules, Big Impact in Cancer Research
Wallchart
Small Molecules, Big Impact in Cancer Research

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Quality Statement:

PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED.

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