Dibutyryl-cAMP
cAMP pathway activator; Activates cAMP-dependent protein kinases
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Dibutyryl-cAMP -
Dibutyryl-cAMP -
Label for Dibutyryl-cAMP -
Label for Dibutyryl-cAMP -
Label for Dibutyryl-cAMP
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Overview
Dibutyryl-cAMP is a cell-permeable cyclic AMP (cAMP) analog that activates cAMP-dependent protein kinases (Schwede et al.). This product is supplied as the sodium salt of the molecule.
DIFFERENTIATION
· Suppresses experimental autoimmune encephalomyelitis development by reducing demyelination and mobilizing neural stem cells in the subventricular zone towards the demyelinated plaques (Khezri et al.).
· Induces intrinsic axon growth in peripheral and central nervous systems, and morphological differentiation of astrocytes (Knott et al.; Imamura & Ozawa).
· Stimulates neurite outgrowth in PC12 cells (Maruoka et al.).
DIFFERENTIATION
· Suppresses experimental autoimmune encephalomyelitis development by reducing demyelination and mobilizing neural stem cells in the subventricular zone towards the demyelinated plaques (Khezri et al.).
· Induces intrinsic axon growth in peripheral and central nervous systems, and morphological differentiation of astrocytes (Knott et al.; Imamura & Ozawa).
· Stimulates neurite outgrowth in PC12 cells (Maruoka et al.).
Alternative Names:
Bucladesine; DC 2797
CAS Number:
16980-89-5
Chemical Formula:
C₁₈H₂₃N₅O₈P · Na
Molecular Weight:
491.4 g/mol
Purity:
≥ 95%
Pathway:
cAMP
Target:
cAMP-Dependent Kinase
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PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED. FOR ADDITIONAL INFORMATION ON QUALITY AT STEMCELL, REFER TO WWW.STEMCELL.COM/COMPLIANCE.