SU5402

MEK/ERK pathway inhibitor; Inhibits VEGFR2, FGFR1, and PDGFRB
Catalog #
73912_C
MEK/ERK pathway inhibitor; Inhibits VEGFR2, FGFR1, and PDGFRB
From: 49 USD

Overview

SU5402 is a potent and selective inhibitor of vascular endothelial growth factor receptor 2 (VEGFR-2), fibroblast growth factor receptor 1 (FGFR-1), and platelet-derived growth factor receptor beta (PDGFRB) with IC50 = 0.02, 0.03, and 0.51 µM, respectively (Sun et al.).
Alternative Names
Not applicable
Cell Type
Cancer Cells and Cell Lines, Hybridomas, Pluripotent Stem Cells
Species
Human, Mouse, Rat, Non-Human Primate, Other
Application
Maintenance
Area of Interest
Antibody Development, Cancer Research, Disease Modeling, Hybridoma Generation, Immunology, Stem Cell Biology
CAS Number
215543-92-3
Chemical Formula
C₁₇H₁₆N₂O₃
Molecular Weight
296.3 g/mol
Purity
≥ 95%
Pathway
MEK/ERK
Target
FGFR, PDGFR

Related Products

Scientific Resources

Product Documentation

Document Type Product Name Catalog # Lot # Language
Document Type
Product Information Sheet 1
Product Name
SU5402
Catalog #
73912, 73914
Lot #
For orders placed 2019-11-26 or earlier
Language
English
Document Type
Product Information Sheet 2
Product Name
SU5402
Catalog #
73912, 73914
Lot #
For orders placed 2019-11-27 or later
Language
English
Document Type
Safety Data Sheet
Product Name
SU5402
Catalog #
73912, 73914
Lot #
All
Language
English

Educational Materials(6)

Brochure
Cytokines, Chemokines and Growth Factors
Brochure
Small Molecules for Stem Cell Research
Brochure
Small Molecules for Cancer Research
Wallchart
Small Molecules, Big Impact in Pluripotent Stem Cell Research
Wallchart
Small Molecules, Big Impact in Cancer Research
Wallchart
Human Immune Cytokines

Product Applications

This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.

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