SU5402
MEK/ERK pathway inhibitor; Inhibits VEGFR2, FGFR1, and PDGFRB
Overview
SU5402 is a potent and selective inhibitor of vascular endothelial growth factor receptor 2 (VEGFR-2), fibroblast growth factor receptor 1 (FGFR-1), and platelet-derived growth factor receptor beta (PDGFRB) with IC50 = 0.02, 0.03, and 0.51 µM, respectively (Sun et al.).
Alternative Names
Not applicable
Cell Type
Cancer Cells and Cell Lines, Hybridomas, Pluripotent Stem Cells
Species
Human, Mouse, Rat, Non-Human Primate, Other
Application
Maintenance
Area of Interest
Antibody Development, Cancer Research, Disease Modeling, Hybridoma Generation, Immunology, Stem Cell Biology
CAS Number
215543-92-3
Chemical Formula
C₁₇H₁₆N₂O₃
Molecular Weight
296.3 g/mol
Purity
≥ 95%
Pathway
MEK/ERK
Target
FGFR, PDGFR
Related Products
Related Products
Scientific Resources
Product Documentation
| Document Type | Product Name | Catalog # | Lot # | Language |
|---|---|---|---|---|
|
Document Type
Product Information Sheet 1
|
Product Name
SU5402
|
Catalog # 73912, 73914 |
Lot # For orders placed 2019-11-26 or earlier |
Language English |
|
Document Type
Product Information Sheet 2
|
Product Name
SU5402
|
Catalog # 73912, 73914 |
Lot # For orders placed 2019-11-27 or later |
Language English |
|
Document Type
Safety Data Sheet
|
Product Name
SU5402
|
Catalog # 73912, 73914 |
Lot # All |
Language English |
Educational Materials(6)
Brochure
Cytokines, Chemokines and Growth Factors
Brochure
Small Molecules for Stem Cell Research
Brochure
Small Molecules for Cancer Research
Wallchart
Small Molecules, Big Impact in Pluripotent Stem Cell Research
Wallchart
Small Molecules, Big Impact in Cancer Research
Wallchart
Human Immune Cytokines
Product Applications
This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.
Research Area
Workflow Stages
Workflow Stages for
B Cell Research
Workflow Stages for
Hybridoma Production
Workflow Stages for
Mouse Pluripotent Stem Cell Research
Quality Statement:
PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED. FOR ADDITIONAL INFORMATION ON QUALITY AT STEMCELL, REFER TO WWW.STEMCELL.COM/COMPLIANCE.
