Nature Research Round Table: Identifying Acquired and Background Genetic Variants in Human Pluripotent Stem Cells
Dr. Florian Merkle from the University of Cambridge talks about the implications of quality control during gene editing, in particular genetic variants that arise during routine culture and genetic variants that might have been acquired during the process of gene editing. This presentation and the following Q&A session were moderated by Dr. Alex Alderton from the Wellcome Trust Sanger Institute.
This presentation was part of a Round Table series titled “Challenges in Ensuring hPSC Quality”, hosted in partnership with Nature Research. Global experts gathered at the Springer Nature headquarters in London, UK, to tackle some of the most pertinent issues impacting the use of human pluripotent stem cells (hPSCs), ranging from fundamental biology research to therapeutic applications. Explore the full series here.
Related Multimedia
-
Nature Research Round Table: Genome Editing in Human Pluripotent Stem Cells
Publish Date: November 01, 2019 -
Nature Research Round Table: The Process of Human Pluripotent Stem Cell Adaptation
Publish Date: November 01, 2019 -
Nature Research Round Table: Best Practices for the QC of Genome-Edited hPSC Lines - Panel Discussion
Publish Date: November 01, 2019
Item added to your cart

Nature Research Round Table: Identifying Acquired and Background Genetic Variants in Human Pluripotent Stem Cells
Explore Our Products
-
Feeder-free, animal component-free culture medium for maintenance of human ES and iPS cells
-
Enhanced green fluorescent protein (eGFP)-tagged Cas9 nuclease for the generation of double-strand breaks in CRISPR-Cas9 genome editing
-
Defined supplement for single-cell cloning of human ES and iPS cells
-
qPCR analysis kit for detecting the majority of karyotypic abnormalities reported in human ES and iPS cells