Semi-Solid Cloning with ClonaCell™
Cloning hybridomas and CHO cells can be done faster and more efficiently using semi-solid cloning, compared to traditional cloning techniques. During semi-solid cloning, individual cells are immobilized within a viscous, semi-solid medium and grow into discrete, monoclonal colonies. Picking these colonies enables isolation of a large number of diverse clones with a high probability of monoclonality. Semi-solid cloning reduces or eliminates empty cloning wells, allowing more clones to be isolated using fewer resources. Semi-solid cloning also facilitates easy isolation of both fast- and slow-growing clones, thus increasing clonal diversity and making it easier to find rare, high-producing or functional clones.
Publish Date: February 14, 2014 Views: 3285
Publish Date: December 02, 2011 Views: 16322
Publish Date: July 17, 2013 Views: 6315
A Smarter Way To Clone: What You Don't Know About Limiting Dilution Can Hurt Your Probability of MonoclonalityPublish Date: February 03, 2012 Views: 199