Anti-Human CD326 (EpCAM) Antibody, Clone 323/A3
Mouse monoclonal IgG1 antibody against human CD326 (EpCAM)
Overview
The 323/A3 antibody reacts with the human epithelial cell adhesion molecule (EpCAM or CD326), an ~40 kDa type I transmembrane glycoprotein which functions as a homophilic and Ca++-independent adhesion molecule. EpCAM has roles in several cellular processes, including signaling, migration, proliferation, and differentiation. It is expressed early during erythrogenesis and has been identified as a stem cell marker. The EpCAM protein is found on the basolateral membrane of most normal epithelial cells and is highly expressed in bone marrow, colon, and lung. EpCAM is not expressed on mesothelial cells or mesotheliomas, and so is widely used as a diagnostic marker to distinguish mesothelioma and carcinoma cells, as well as serving as a target for immunotherapeutic treatment of carcinomas.
Subtype
Primary Antibodies
Target Antigen
CD326 (EpCAM)
Alternative Names
EGP2, EpCAM, Epithelial cell adhesion molecule, ESA, TACSTD1, TROP-1
Reactive Species
Human
Conjugation
Unconjugated
Host Species
Mouse
Cell Type
Mammary Cells
Species
Human
Application
Cell Isolation, Flow Cytometry, Immunocytochemistry, Immunohistochemistry
Area of Interest
Epithelial Cell Biology, Stem Cell Biology
Clone
323/A3
Gene ID
4072
Isotype
IgG1, kappa
Related Products
Related Products
Scientific Resources
Product Documentation
| Document Type | Product Name | Catalog # | Lot # | Language |
|---|---|---|---|---|
|
Document Type
Product Information Sheet
|
Product Name
Anti-Human CD326 (EpCAM) Antibody, Clone 323/A3
|
Catalog #
60146 |
Lot #
All |
Language
English |
|
Document Type
Safety Data Sheet 1
|
Product Name
Anti-Human CD326 (EpCAM) Antibody, Clone 323/A3
|
Catalog #
60146 |
Lot #
All |
Language
English |
|
Document Type
Safety Data Sheet 2
|
Product Name
Anti-Human CD326 (EpCAM) Antibody, Clone 323/A3
|
Catalog #
60146 |
Lot #
All |
Language
English |
Educational Materials (1)
Brochure
Reliable Antibodies for Your Research
Product Applications
This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.
Research Area
Workflow Stages
Workflow Stages for
hPSC-Derived Mesoderm Cell Research
Quality Statement:
PRODUCTS ARE FOR RESEARCH USE ONLY AND NOT INTENDED FOR HUMAN OR ANIMAL DIAGNOSTIC OR THERAPEUTIC USES UNLESS OTHERWISE STATED. FOR ADDITIONAL INFORMATION ON QUALITY AT STEMCELL, REFER TO WWW.STEMCELL.COM/COMPLIANCE.
