Collagenase Type II

For digestion of native collagen fibrils
Catalog #
07418_C
For digestion of native collagen fibrils
From: 84 USD

Overview

Collagenase is a protease consisting of a single polypeptide chain approximately 1,000 amino acid residues in length. Collagenase is capable of digesting native collagen fibrils commonly found in connective tissues and therefore is frequently used for tissue dissociation. Collagenase preparations contain the activity of several proteases, including collagenase, caseinase, clostripain, and trypsin (Kessler & Yaron). Collagenase Type II contains high levels of protease activity, especially clostripain, and has been used for the digestion of lung (You & Brody; Comhair et al.), kidney (Valente et al.), liver (Linghor et al.), thymus (Vandenabeele et al.), endothelial cells (Patel et al.) and mesenchymal stem cells (Steigman & Fauza).
Subtype
Enzymatic
Alternative Names
Clostridium histolyticum collagenase; Collagenase 2; Collagenase Type 2; Collagenase II
Cell Type
Endothelial Cells, Hepatic Cells, Mesenchymal Stem and Progenitor Cells, T Cells, CD4+
Species
Human, Mouse, Rat, Non-Human Primate, Other
Area of Interest
Cancer, Endothelial Cell Biology, Epithelial Cell Biology, Immunology, Stem Cell Biology
Molecular Weight
68 - 130 kDa

Scientific Resources

Product Documentation

Document Type Product Name Catalog # Lot # Language
Document Type
Product Information Sheet
Product Name
Collagenase Type II
Catalog #
07418, 07419, 100-0678
Lot #
All
Language
English
Document Type
Safety Data Sheet
Product Name
Collagenase Type II
Catalog #
07418, 07419, 100-0678
Lot #
All
Language
English

Educational Materials (1)

Wallchart
Human Immune Cytokines

Product Applications

This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s). Explore these workflows to learn more about the other products we offer to support each research area.

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