Collagenase Type II

For digestion of native collagen fibrils

Collagenase Type II

For digestion of native collagen fibrils

From: 98 USD
Catalog #
07418_C
For digestion of native collagen fibrils
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Overview

Collagenase is a protease consisting of a single polypeptide chain approximately 1,000 amino acid residues in length. Collagenase is capable of digesting native collagen fibrils commonly found in connective tissues and therefore is frequently used for tissue dissociation. Collagenase preparations contain the activity of several proteases, including collagenase, caseinase, clostripain, and trypsin (Kessler & Yaron). Collagenase Type II contains high levels of protease activity, especially clostripain, and has been used for the digestion of lung (You & Brody; Comhair et al.), kidney (Valente et al.), liver (Linghor et al.), thymus (Vandenabeele et al.), endothelial cells (Patel et al.) and mesenchymal stem cells (Steigman & Fauza).
Subtype
Enzymatic
Cell Type
Endothelial Cells, Hepatic Cells, Mesenchymal Stem and Progenitor Cells, T Cells, CD4+
Species
Human, Mouse, Non-Human Primate, Other, Rat
Area of Interest
Cancer, Endothelial Cell Biology, Epithelial Cell Biology, Immunology, Stem Cell Biology

Protocols and Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type
Product Name
Catalog #
Lot #
Language
Catalog #
07419, 07418, 100-0678
Lot #
All
Language
English
Document Type
Safety Data Sheet
Catalog #
07419, 07418, 100-0678
Lot #
All
Language
English

Applications

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Resources and Publications

Educational Materials (1)