Anti-SHIP (C-Terminus) Antibody, Polyclonal

Rabbit polyclonal antibody against human, mouse SHIP

Anti-SHIP (C-Terminus) Antibody, Polyclonal

Rabbit polyclonal antibody against human, mouse SHIP

From: 500 USD
Catalog #
60144_C
Rabbit polyclonal antibody against human, mouse SHIP

Overview

SHIP (C-terminus) is critical for the function of SHIP protein. SH2-containing inositol phosphatase (SHIP) is a 145 kDa hematopoietic-restricted protein that becomes tyrosine-phosphorylated and associated with the adaptor protein, Shc, following cytokine, growth factor, chemokine, and immunoreceptor stimulation. SHIP also hydrolyzes the critical phosphatidylinositol (PI)-3-kinase (PI3K)-generated second messenger, PI-3,4,5-P3 (PIP3), to PI-3,4-P2 1,2 and therefore acts as an important negative regulator of the PI3K pathway. This antibody reacts with mouse and human full-length 145 kDa SHIP protein.
Subtype
Primary Antibodies
Target Antigen
SHIP
Alternative Names
phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1; p150Ship; SHIP1; SHIP-1; s-SHIP; SIP-145
Reactive Species
Human, Mouse
Conjugation
Unconjugated
Host Species
Rabbit
Cell Type
Granulocytes and Subsets, Lymphocytes, Myeloid Cells
Species
Human, Mouse
Application
Immunoblotting, Immunoprecipitation
Area of Interest
Immunology
Clone
Not applicable
Gene ID
3635 (human), 16331 (mouse)
Isotype
Not applicable

Scientific Resources

Product Documentation

Find supporting information and directions for use in the Product Information Sheet or explore additional protocols below.

Document Type
Product Name
Catalog #
Lot #
Language
Catalog #
60144
Lot #
All
Language
English
Document Type
Safety Data Sheet
Catalog #
60144
Lot #
All
Language
English

Data and Publications

Western blot analysis of total cell lysates from human TF-1 cells (lane 1), mouse WEHI-231 cells (lane 2) and mouse bone marrow derived mast cells (BMMCs; lane 3) with Anti-SHIP (C-Terminus) Antibody, Polyclonal (1:1000 dilution). SHIP has a predicted molecular mass of 145 kDa.

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