Whole blood comprises plasma, red blood cells, platelets, and nucleated white blood cells. Enriched leukapheresis products collected from normal peripheral blood, such as leukopaks and leukocyte reduction system (LRS) cones, consist of a larger number of peripheral blood mononuclear cells (PBMCs) compared to whole blood. Depending on the cell type you want to isolate and the starting blood sample source, different techniques are used to process and prepare the starting blood sample for downstream cell isolation. Explore below to find protocols for processing whole blood samples, leukopaks, LRS cones, as well as methods for downstream cell separation.
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