Identifying Acquired and Background Genetic Variants in Human Pluripotent Stem Cells

Dr. Florian Merkle from the University of Cambridge talks about the implications of quality control during gene editing, in particular genetic variants that arise during routine culture and genetic variants that might have been acquired during the process of gene editing. This presentation and the following Q&A session were moderated by Dr. Alex Alderton from the Wellcome Trust Sanger Institute.

This presentation was part of a Round Table series titled “Challenges in Ensuring hPSC Quality”, hosted in partnership with Nature Research. Global experts gathered at the Springer Nature headquarters in London, UK, to tackle some of the most pertinent issues impacting the use of human pluripotent stem cells (hPSCs), ranging from fundamental biology research to therapeutic applications. Explore the full series here.
Publish Date: November 01, 2019 Views: 4